This is a 3D printed Biologic Model of a Bacterial ArcAB-TolC Efflux Pump colored to match the academic publication An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump.
Bacterial efflux pumps confer multidrug resistance by transporting diverse antibiotics from the cell. In Gram-negative bacteria, some of these pumps form multi-protein assemblies that span the cell envelope. Within the transport-activated state, the channel remains open even though the pump cycles through three distinct conformations. Collectively, our data provide a dynamic mechanism for the assembly and operation of the AcrAB-TolC pump.
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Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating.