SARS-CoV-2 RNA Polymerase inhibited by Remdesivir

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Model Description

Biologic Model of SARS-CoV-2 RNA Polymerase inhibited by Remdesivir 7BV2 3D printed in full-color sandstone.

Protein Description

The replication of SARS-CoV-2 requires the viral RNA-dependent RNA polymerase (RdRp tinted Blue), a target of the antiviral drug, Remdesivir (Colored by Atom type). The complex structure reveals that the partial double-stranded RNA template (Red) is inserted into the central channel of the RdRp where Remdesivir is covalently incorporated into the primer strand (Magenta) at the first replicated base pair and terminates chain elongation.