DPP-4 in Complex with Inhibitor 2RGU

  • Sale
  • Regular price $60.11


3D print of Depiptidyl Peptidase IV (DPP-4) in Complex with Small Molecule Inhibitor. The protein model of DPP-4 is colored according to the protein's bFactor. Isolated and colored by atom type is the active binding site in the interior pocket of DPP-4. 

Protein Description

A new chemical class of potent DPP-4 inhibitors structurally derived from the xanthine scaffold for the treatment of type 2 diabetes has been discovered and evaluated. Systematic structural variations have led to 1 (BI 1356), a highly potent, selective, long-acting, and orally active DPP-4 inhibitor that shows considerable blood glucose lowering in different animal species. 1 is currently undergoing clinical phase IIb trials and holds the potential for once-daily treatment of type 2 diabetics.

For international customers outside the US, please visit the model on our 3D printing service's international website: LINK

Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating.

Created from PDB ID: 2RGU