DXP Synthase-Closed 60UV

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Biologic model of DXP Synthase-Closed 60UV 3D printed in full-color sandstone.

Protein Description

DXPS synthase uses thiamine diphosphate (ThDP) to convert pyruvate and D-glyceraldehyde 3‑phosphate (D-GAP) into 1-deoxy-D-xylulose 5-phosphate (DXP), an essential bacterial metabolite. DXP is not utilized by humans; hence, DXPS has been an attractive antibacterial target.