Biologic Model of Mus81 DNA Complex 3D printed in full-color sandstone visualizing Mus81's hydrophicity (blue-red) and DNA (Greens).
Protein Description
The Mus81-Eme1 endonuclease plays a critical role in during DNA repair. Formation of DNA complex reveals that Mus81-Eme1 undergoes gross substrate-induced conformational changes that reveal two key features: (i) a hydrophobic wedge of Mus81 that separates pre- and post-nick duplex DNA and (ii) a "5' end binding pocket" that hosts the 5' nicked end of post-nick DNA.
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Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating. Natural finish does not.
Created from PDB ID 4P0R.
