Helicases move on DNA coordinated by well-characterized helicase motifs. However, the translocation along single-stranded DNA (ssDNA) may be loosely or tightly coupled. After 3D structural analysis shows a homology sequence that tightly couples translocation to strand separation.
Model Description
Biologic Model of Phage T4 Helicase bound to Single-Stranded DNA and 3D printed in full-color nylone. Ribbon model color-coded by secondary structures and single-stranded colored DNA purple.
Created from PDB ID: 3upu